HEMEL HEMPSTEAD, United Kingdom, 24 July, 2025 — Boston Scientific Corporation (NYSE: BSX) today announced CE mark and introduction in Europe of the Intracept™ Intraosseous Nerve Ablation System. The Intracept system is the only treatment specifically designed to target the basivertebral nerve for the relief of chronic vertebrogenic pain, offering a new treatment option for patients affected by this type of low back pain. The minimally invasive procedure uses targeted radiofrequency energy to stop the basivertebral nerve from carrying pain signals to the brain, with 75 percent of patients experiencing long-lasting improvements in pain and back function after a single Intracept procedure.¹

The first commercial Intracept procedure was performed by a team at Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, in the United Kingdom led by Dr. David McKean, consultant musculoskeletal radiologist.

Almost six million people are suffering from chronic low back pain (CLBP) in the U.K., and it is the second leading cause of disability globally. Vertebrogenic pain is a distinct type of CLBP, caused by damage to the vertebral endplates, the interface between the disc and the vertebral body. Approximately one in six people with CLBP experience vertebrogenic pain.² Typical symptoms include unrelenting pain in the centre of the lower back that worsens with certain movements or prolonged sitting. With the Intracept system, physicians can offer these patients a treatment that has been demonstrated to be safe, effective and long lasting.

“Our aim is to deliver outstanding care, and the Intracept system allows us to provide relief to patients with vertebrogenic low back pain and improve their quality of life,” said Dr. McKean. “With this first purpose-built treatment for vertebrogenic pain, we can serve our patients in a targeted and precise way.”

In clinical studies, patients experienced significant improvements in pain and back function at five years after a single treatment.³ As of June 2025, the Intracept procedure has already changed the lives of more than 50,000 patient across the United States, where the device received FDA clearance in 2016.

"Vertebrogenic pain can significantly impact people’s quality of life, limiting mobility and causing severe discomfort for those affected,” said Vincent Sourdaine, vice president, Neuromodulation in Europe, Middle East and Africa (EMEA) at Boston Scientific. “With the Intracept system, we have added a further evidence-based treatment option to our growing portfolio of therapies for chronic pain management, offering our customers more options to help these patients.”

Boston Scientific is initiating a limited market release of the Intracept system in Europe, the Middle East and Africa over the coming months.

About Boston Scientific
Boston Scientific transforms lives through innovative medical technologies that improve the health of patients around the world. As a global medical technology leader for more than 45 years, we advance science for life by providing a broad range of high-performance solutions that address unmet patient needs and reduce the cost of healthcare. Our portfolio of devices and therapies helps physicians diagnose and treat complex cardiovascular, respiratory, digestive, oncological, neurological and urological diseases and conditions. Learn more at www.bostonscientific.eu and connect on LinkedIn and X, formerly Twitter.

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CONTACTS:
Uchenna Izundu
Media Relations
+44 (0) 7772 404 018
uchenna.izundu@bsci.com